Designing ecologically optimized pneumococcal vaccines using population genomics
نویسندگان
چکیده
منابع مشابه
Pneumococcal conjugate vaccines
To assess whether certain serogroups of Streptococcus pneumoniae are preferentially associated with specific disease manifestations, we analyzed all recent pneumococcal disease studies and assessed the relative frequency of isolation of each serogroup by clinical site (as a proxy for different disease states). In all age groups, serogroups 1 and 14 were more often isolated from blood, and serog...
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ژورنال
عنوان ژورنال: Nature Microbiology
سال: 2020
ISSN: 2058-5276
DOI: 10.1038/s41564-019-0651-y